Technische Universität München

The Entrepreneurial University

There are some adverse effects reported in the musculoskeletal system, e.g. causing bone fractures, tendon pathology and rhabdomyolysis.
If applicated at children age, AAS induce a premature closure of the epiphysis resulting in growth retardation. Furthermore the steroids cause changes in the tendon structure itself. AAS appear to induce reversible changes in the biomechanical properties of tendon producing a stiff, less elastic tendon. It is possible that the rapid strength adaptations being produced by AAS in skeletal muscle are not simultaneously accompanied by slower adapting, less vascular tendon structures, making tendons the weakest link in the chain. Rhabdomyolysis or acute skeletal muscle destruction may occur after intake of anabolic androgenic steroids in combination with weight-training programmes.